从“火克金，金侮火”论治心血管疾病

从中医藏象的生理、病理、临床3个方面及联系现代医学论述五行中“火克金,金侮火”的关系,从而丰富中医基础理论及指导心血管疾病临床防治均有一定意义。     

中医肾与其他四脏关系的研究与思考

归纳和分析历代医家有关中医肾与心、肝、脾、肺关系,梳理近20年来国内学者结合现代生理学、病理学观点对这些学说的研究及临床应用,并讨论存在的问题和发展思路。     

孙伟护肾养阴法治疗慢性肾脏病

肾虚是慢性肾脏病发生发展的基础,由于先天不足、过食温燥、劳逸失度、情志内伤、久病迁延等因素,肾阴虚,乃至气阴两虚等证在临证中频频涉及。孙伟教授提出了护肾养阴法,在治疗上强调补益肾阴,兼顾五脏,弥补亏损之元阴。常用药有制黄精、山萸肉、旱莲草、女贞子、石斛、玉竹、黄芪、太子参等,慎用辛热之品以防劫阴太过,损耗肾阴。善用杜仲、川续断、菟丝子等平补肾阳之品,以期阳中求阴,并适当佐以活血化瘀药物,如当归、丹参、益母草、牛膝等,不致滋阴太过加重湿浊内蕴,使得补而不滞,养阴而不助邪。整体上更注重以养为护、养护并重,从而达到阴阳调和、延缓疾病进展的目的。     

《内经》五郁之治在儿科临床中的应用

《内经》五郁之治,是针对五气太过而致五脏气郁所提出的治疗法则,从五郁治法概述以及相应木郁达之、火郁发之、土郁夺之、金郁泄之、水郁折之五法进行了理论阐释和临床运用举例。指出五郁之治不仅适用于内科常见病证的辨治,对于儿科临床常见病证的辨治亦有很好的指导意义。     

五神脏论治注意力缺陷多动障碍

针对注意力缺陷多动障碍的发生、发展与心、肝、脾、肺、肾的关系,从五神脏切入谈其辨证论治.     

旷惠桃教授治疗干燥综合征临床经验

介绍湖南省名老中医旷惠桃教授治疗干燥综合征的临床经验,认为该病属中医学"燥痹"范畴。旷教授认为燥痹之标为燥热,病机则在于气血阴津亏虚,燥、热内生,脏腑诸窍失养,临床多见肺胃阴虚、肝肾阴虚证,故而临床治疗重在滋补肺胃肝肾,脏腑兼顾,随证加减。并附验案1则,以资佐证。     

牙周炎对肥胖小鼠内脏重量和系数的影响

目的 探索肥胖状态下牙周炎对模型动物的内脏重量和系数的影响。方法 将64只C57BL/6J小鼠随机分为高脂饲料（HFD）组（n=36）和低脂饲料（LFD）（n=28）组,HFD组诱导肥胖至处死,LFD组作为正常体重对照。诱导16周,两饲料组均再分为牙周炎（P）组和对照（C）组,P组用长有牙龈卟啉单胞菌的丝线分别结扎5、10 d诱导牙周炎,C组做假性结扎。结扎后处死小鼠,分离内脏称重并计算内脏系数。结果 与LFD组相比,HFD组上调内脏脂肪和脾的重量、系数（P<0.05）,上调肝、肾重量（P<0.05）,下调肝系数和肾系数（P<0.01）。HFD组中,P组相对于C组下调脾重量和系数（P<0.05）,而结扎10 d相对于结扎5 d上调脾重量和系数（P<0.05）。结论 牙周炎可影响肥胖模型动物内脏（特别是脾脏）的大体形态,该现象在肥胖与牙周炎的相互关系中可能具有免疫代谢学层面的病理意义。     

Chronic Idiopathic Cough: A Discrete Clinical Entity?

STUDY OBJECTIVES: Despite the success of specialist cough clinics, there is increasing recognition of a subgroup of chronic coughers in whom a diagnosis cannot be made even after thorough, systematic investigation. We call this condition chronic idiopathic cough (CIC). The aim of this study is to compare the clinical characteristics of CIC patients with those of coughers in whom a diagnosis has been established (non-CIC) to see if there is a recognizable clinical pattern that distinguishes CIC from non-CIC. DESIGN: Retrospective analysis of the medical records of chronic cough patients. SETTING: The Royal Brompton Hospital Chronic Cough Clinic, London. PATIENTS: One hundred patients with chronic cough referred to the Royal Brompton Hospital Cough Clinic between October 2000 and February 2004. RESULTS: Seventy-one percent of all patients were female. Median age was 57 years (range, 19 to 81 years), with a median duration of symptoms of 48 months (range, 2 to 384 months). The primary diagnoses were CIC (42%), postnasal drip syndromes (22%), gastroesophageal reflux disease (16%), asthma (7%), and others (13%). In CIC patients, the median age at referral, age at onset of cough, and proportion of females did not differ significantly from non-CIC patients. CIC patients had a longer median duration of cough (72 months vs 24 months, p = 0.002), were more likely to report an upper respiratory tract infection (URTI) as the initial trigger of their cough (48% vs 24%, p = 0.0014), and had a significantly lower cough threshold in response to capsaicin (log concentration of capsaicin required to induce five or more coughs, - 0.009 vs 0.592, p = 0.032) than non-CIC patients. CONCLUSIONS: Patients with CIC commonly describe a URTI that initiates their cough, which then lasts for many years, and they demonstrate an exquisitely sensitive cough reflex. We believe that CIC may be a distinct clinical entity with an as-yet unidentified underlying pathology.     

产后盆底训练对预防女性早期盆底功能障碍的价值研究

目的：了解产后盆底训练对预防女性早期盆底障碍的临床价值。方法：住院分娩的产妇240名分成研究组（118例）和观察组（122例）。研究组产后42d采用法国PHENIX盆底肌肉康复系统进行盆底肌肉训练,对照组进行一般产后随访,两组分别以产后42d及产后3、6个月进行随访,项目包括测定盆底肌肉张力及问卷调查尿失禁的发生情况,并进行POP～Q分度评估。结果：研究组产后3、6个月阴道静息压、阴道收缩压及阴道收缩持续时问均高于对照组,差异有高度统计学意义（P〈0．01）;研究组产后3、6个月尿失禁的发生率低于对照组,两组比较差异均有统计学意义（均P〈0．05）。两组产后3、6个月随访期间无脏器Ⅲ度脱垂情况发生。结论：产后早期盆底训练可减少尿失禁的发生,改善盆腔脏器脱垂,值得临床推广应用。     

大学生人格特征对其博客行为的Logistic回归分析

目的:探讨大学生人格特征与博客创作行为的关系。方法:采用自编的大学生博客行为调查表和NEO-FFI大五人格问卷对401名在校大学生进行调查。结果:通过Logistic回归分析显示,大五人格中的经验开放性(β=0.414,wald=6.627,P<0.05)和尽责性(β=0.509,wald=5.226,P<0.05)特质对大学生博客行为具有显著的正向预测作用。结论:人格特征可以作为是否参与博客行为的有效预测变量。